Using Stem Cells to Improve Motor Function

Brian Wainger, MD, PhD, is developing a novel therapy to help improve motor outcomes in nerve injury and ALS in collaboration with Justin Brown, MD in the Department of Neurosurgery. The strategy is to transplant engineered motor neurons that have been derived in the laboratory from human stem cells.

Investigating Therapeutic Options to Increase STMN2 Levels

Researchers at the Sean M. Healey & AMG Center for ALS, along with their colleagues, demonstrated that pharmacological compounds and gene therapy that increase the levels of STMN2 can restore the ability of neurons to grow axons after injury.