Research Portfolio
Research Portfolio
Brain-Computer Interfaces
Leigh Hochberg, MD, PhD
There is an urgent need to ensure people with ALS will never lose the ability to communicate. Led by Leigh Hochberg, MD, PhD and the extraordinary BrainGate team at Mass General, together with an unmatched multi-institutional and multidisciplinary team, we are getting closer to achieving that goal.
All
research
Address the
root cause
Discover
novel therapies
Enhance
neuroplasticity
Implement
neurotechnology
Pioneer disruptive
approaches
Repair and Regeneration Research
Brain-Computer Interfaces
Leigh Hochberg, MD, PhD
There is an urgent need to ensure people with ALS will never lose the ability to communicate. Led by Leigh Hochberg, MD, PhD and the extraordinary BrainGate team at Mass General, together with an unmatched multi-institutional and multidisciplinary team, we are getting closer to achieving that goal.
Investigating Therapeutic Options to Increase STMN2 Levels
Clotilde Lagier-Tourenne, MD, PhD
Researchers at the Sean M. Healey & AMG Center for ALS, along with their colleagues, demonstrated that pharmacological compounds and gene therapy that increase the levels of STMN2 can restore the ability of neurons to grow axons after injury.
Using Stem Cells to Improve Motor Function
Brian Wainger, MD, PhD
Brian Wainger, MD, PhD, is developing a novel therapy to help improve motor outcomes in nerve injury and ALS in collaboration with Justin Brown, MD in the Department of Neurosurgery. The strategy is to transplant engineered motor neurons that have been derived in the laboratory from human stem cells.
The Impact of Gene Fusions on ALS Disease Progression
Ghazaleh Sadri-Vakili, MD, PhD
We predict that ALS-specific gene fusions may improve many aspects of clinical care as already
demonstrated in the field of oncology and are now working to understand how the fusions effect ALSdisease progression.
All research
Address the
root cause
Discover
novel therapies
Enhance
neuroplasticity
Implement
neurotechnology
Pioneer disruptive
approaches
Brain-Computer Interfaces
Leigh Hochberg, MD, PhD
There is an urgent need to ensure people with ALS will never lose the ability to communicate. Led by Leigh Hochberg, MD, PhD and the extraordinary BrainGate team at Mass General, together with an unmatched multi-institutional and multidisciplinary team, we are getting closer to achieving that goal.
Investigating Therapeutic Options to Increase STMN2 Levels
Clotilde Lagier-Tourenne, MD, PhD
Researchers at the Sean M. Healey & AMG Center for ALS, along with their colleagues, demonstrated that pharmacological compounds and gene therapy that increase the levels of STMN2 can restore the ability of neurons to grow axons after injury.
Using Stem Cells to Improve Motor Function
Brian Wainger, MD, PhD
Brian Wainger, MD, PhD, is developing a novel therapy to help improve motor outcomes in nerve injury and ALS in collaboration with Justin Brown, MD in the Department of Neurosurgery. The strategy is to transplant engineered motor neurons that have been derived in the laboratory from human stem cells.
The Impact of Gene Fusions on ALS Disease Progression
Ghazaleh Sadri-Vakili, MD, PhD
We predict that ALS-specific gene fusions may improve many aspects of clinical care as already
demonstrated in the field of oncology and are now working to understand how the fusions effect ALSdisease progression.
